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This, in turn, stimulates local inflammation in the renal microenvironment, causing damage to nearby renal cells such as podocytes, mesangial cells, and endothelial cells, as well as causing local and systemic inflammation [5,6]

Tirzepatide acts on two targets in the body, leading to greater initial weight loss, which also may translate to regaining more weight after switching to orforglipron

Continue following Ozempic/GLP-1 trends here

Our Family Health Care team will work closely with you to determine the most appropriate medication and dosing schedule based on your health status, weight loss goals, and how you respond to treatment

Research on how long semaglutide takes to work shows that steady-state levels and consistent results require, above all, consistent dosing

About the author Courtney Vinopal Courtney Vinopal is a senior reporter for HR Brew covering total rewards and compliance.